rats {asreml} | R Documentation

## Reproductive study on rats

### Description

Litter weights of pups from rats given three doses (control, low and high) of an experimental compound affecting reproductive performance.

### Usage

    rats

### Format

A data frame with 6 columns and 322 rows:

Dose

  A factor with 3 levels

Sex

  A factor with 2 levels

littersize

  A covariate

Dam

  A factor with 27 levels

Pup

  A factor with 18 levels

weight

  Individual pup weights in grams

### Details

Thirty female rats (dams) were randomly split into three groups of 10 and each group randomly assigned a dosing level. Three litters had to be dropped from the high dose level.

### References

Dempster AP, Patel CM, Selwyn MR, Roth AJ (1984). “Statistical and Computational Aspects of Mixed Model Analysis.” Journal of the Royal Statist. Series C., 33(2), 203–214.

[Package asreml version 4.1.0.176 Index]